The Toffees go into the game on the back of a 1-1 draw against Brighton, with Wayne Rooney sparing the Merseyside outfit’s blushes.
Ronald Koeman is under increasing pressure after a series of inconsistent matches this season in both the Premier League and Europa League.
They are bottom of Group E, after losing to Atalanta away from home, and drawing with Apollon Limassol at Goodison Park.
However, they will be facing tough opposition in Lyon.
Match details below:
When is Everton vs Lyon?
Everton vs Lyon is on Thursday 19 October.
Kick-off is at 8.05pm.
What channel is Everton vs Lyon on?
The match is live on on BT Sport 2 and BT Sport 4K UHD.
The match will be available to stream on BTSport.com and the BT Sport app.
What is the team news?
Ronald Koeman has a decision to make whether to rest key players with Arsenal visiting on Sunday.
Everton will be is without several key players due to injury, with Seamus Coleman, Ramiro Funes Mori and James McCarthy all long-term absentees.
Aaron Lennon, Yannick Bolasie and Ross Barkley are also sidelined.
What are the latest odds? (Courtesy of Betfair)
Everton – 6/4
Draw – 12/5
Lyon – 15/8
- This will be the first ever competitive meeting between Everton and Lyon.
- Lyon have won just once in their last 11 European matches versus English teams.
- The Toffees have won seven of their last nine games at Goodison Park in European competition.